Atherosclerosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Middle-risk population (5.0%-9.9%) and low-risk population (less than 5.0%) were screened by 10-year ASCVD Morbidity Risk Assessment Table; 2. Adherence to the experimental dietary intervention; 3. Aged from 35 to 65 years; 4. Those who agree to participate in clinical research and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who have been diagnosed as ASCVD (very high risk group); 2. Those who meet one of the following criteria (high risk group) (1)1.8 mmol/l 40 years); (2) Individuals with very high levels of individual risk factors, they included: 1) LDL-C level >=4.9 mmol/l (190 MG/DL) or total cholesterol (TC) level >=7.2 mmol/l (280 MG/DL); 2) Class 3 hypertension; 3) Heavy smoking (>=30 cigarettes/day) . (3) Those with any of the following risk factors: 1) Systolic blood pressure >=160mmhg or diastolic blood pressure >=100mmhg; 2) NON-HDL-C >=5.2 mmol/l (200mg/dl); 3) HDL-C =28kg/m2; 5) Smoking; 3. Ultrasound of the carotid artery showed severe obstruction of blood flow or absence of plaque formation due to plaque in the lumen; 4. Complicated with severe cardiopulmonary insufficiency and Severe Arrhythmia (rapid atrial fibrillation, atrial flutter, paroxysmal ventricular Tachycardia, etc.); 5. Severe hepatic and renal dysfunction; 6. Patients with systemic immune disease, severe infection, malignant tumor, acute coronary syndrome, acute stroke. 7. Allergic constitution or allergic to multiple drugs; 8. Those who have been treated with similar drugs in the past 3 months, and the efficacy of the drugs is difficult to judge; 9. Participate in other clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine;Lipid Metabolism Index;Physical indicators;Comprehensive Metabolic Panel;Carotid ultrasound measurement; | — |
Countries
China
Contacts
Zhuhai Campus, Zunyi Medical University