Digestive disease
Conditions
Interventions
Group A:Immediately after taking the laxative, take simethicone 600mg (half bottle), and then take 600mg (half bottle) back to the room
Group B:Take Simethicone 1200mg immediately after taking the laxative
Group C:Take 600mg of simethicone 1 hour after taking the laxative, and then take another 600mg (half bottle) when you return to the room
Group D:Take Simethicone 1200mg (1 bottle) 1 hour after taking the laxative
Sponsors
Zhongda Hospital Affiliated to Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18-70 years, regardless of gender; 2. Patients undergoing colonoscopy; 3. Voluntarily accept the test and sign the informed consent before the inspection; 4. Patients who can cooperate and perform bowel preparation according to doctor's orders.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of acute heart palpitations and infarction within 6 months; 2. Patients with severe heart, lung, brain and kidney complications; 3. Patients with intestinal obstruction; 4. Patients with a history of chronic constipation; 5. Patients who have undergone colon cancer surgery in the past; 6. Patients during pregnancy and lactation; 7. Patients who are allergic to simethicone or sorbitol and its salts; 8. Those who are participating in other clinical observation trials or have participated in other clinical trials within 60 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Defoaming effect score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal preparation quality score;Detection rate of colonic polyps and adenomatous polyps;Incidence of abdominal distension and other adverse reactions in patients;Operation time of colonoscopy; | — |
Countries
China
Contacts
Public ContactChen Jinxia
Zhongda Hospital Affiliated to Southeast University
Outcome results
None listed