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Clinicopathologic analysis of high-grade B-cell lymphoma with C-MYC and BCL-6 gene rearrangement in the ovary

Clinicopathologic analysis of high-grade B-cell lymphoma with C-MYC and BCL-6 gene rearrangement in the ovary

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047922
Enrollment
Unknown
Registered
2021-06-27
Start date
2021-09-17
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma

Interventions

Gold Standard:1. In situ hybridization (FISH) to detect cases with C-MYC and BCL-6 gene rearrangements
2. The onset site is the ovary.
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Sponsors

First Affiliated Hospital of Army Medical University, PLA
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: The postoperative pathological diagnosis was ''HGBL, double-hit lymphoma''.

Exclusion criteria

Exclusion criteria: 1. Patients where the onset site is not the ovary; 2. Patients with imperfect clinical, imaging and laboratory examinations; 3. Patients without in situ hybridization (FISH) testing; 4. Patients without C-MYC and BCL-6 gene rearrangements were detected by in situ hybridization (FISH).

Design outcomes

Primary

MeasureTime frame
Tumor size;Lactate dehydrogenase;C-MYC fracture probe;BCL-6 fracture probe;Leukocyte differentiation antigen 20;Leukocyte differentiation antigen 3;Leukocyte differentiation antigen 5;Leukocyte differentiation antigen 10;B-cell lymphoma-2;B-cell lymphoma-6;—

Countries

China

Contacts

Public ContactShi Yu

First Affiliated Hospital of Army Medical University, PLA

drshiyu@126.com+86 13512350865

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026