respiratory distress syndrome
Conditions
Interventions
Modified LISA group:Extended administration
Control group:No
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Gestational age<=34 weeks; 2. Meet the RDS diagnostic criteria of "Practical Neonatology" (5th Edition): (1) Progressive dyspnea in premature infants after birth; (2) Consistent with RDS chest X-ray findings.
Exclusion criteria
Exclusion criteria: 1. Children who need endotracheal intubation or have been intubated; 2. Children with respiratory distress caused by severe infection, aspiration pneumonia asphyxia, congenital pneumonia, etc.; 3. Combined with severe congenital malformations (such as congenital pulmonary dysplasia, respiratory malformation, esophageal fistula, etc.); 4. Serious complications such as early-onset sepsis, severe intracranial hemorrhage; 5. Congenital hereditary shooting disease; 6. Endotracheal intubation and mechanical ventilation are required during postnatal resuscitation and exogenous PS has been used before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation rate;Necrotizing enterocolitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Non-invasive ventilation time;Oxygen therapy time;Decreased oxygen saturation;bradycardia;air leak syndrome;bronchopulmonary dysplasia;Retinopathy; | — |
Countries
China
Contacts
Public ContactLiu Rongtian
Shenzhen Second People's Hospital
Outcome results
None listed