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An open study of Levamisole combined with PEG IFN-a-2b in the treatment of chronic hepatitis B

An open study of Levamisole combined with PEG IFN-a-2b in the treatment of chronic hepatitis B

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047873
Enrollment
Unknown
Registered
2021-06-27
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HBV

Interventions

Group 1:Levamisole coating agent + PEG-IFN- a- 2B + nucleoside analogues
Group 2:Levamisole coating agent + PEG-IFN- a- 2B
Group 3:Levamisole coating agent +nucleoside analogues
Group 4: PEG-IFN-a-2b
Group 5:nucleoside analogues

Sponsors

The First Affiliated Hospital of Xinjiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient must sign the informed consent and voluntarily accept the follow-up for at least 24 weeks; 2. Aged 18 to 75 years, gender is not limited; 3. Comply with the indications for antiviral treatment of the "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2019 Edition)"; 4. All patients signed the "Informed Consent" with full knowledge, understanding and voluntariness.

Exclusion criteria

Exclusion criteria: 1. Child-Pugh rating C; 2. Neutrophil count <0.5x10^9/L, or platelets <25x10^9/L; 3. A clear diagnosis of patients with anxiety or depression; 4. Pregnant women and lactating women; 5. Diabetic patients with poor blood sugar control; 6. Patients with poorly controlled hypertension and blood pressure; 7. The investigator believes that there are any other factors that are not suitable for inclusion or that affect subjects participating in or completing the trial.

Design outcomes

Primary

MeasureTime frame
HBV DNA;the quantitation of HBV markers;

Countries

China

Contacts

Public ContactLu Xiaobo

The First Affiliated Hospital of Xinjiang Medical University

xjykdluxiaobo@126.com+86 15999176213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026