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Study on the Mechanism of Acupuncture therapy for postoperative Gastrointestinal dysfunction, and relationship with the regulation of Brain-gut Peptide and inflammatory factors

Study on the Mechanism of Acupuncture therapy for postoperative Gastrointestinal dysfunction, and relationship with the regulation of Brain-gut Peptide and inflammatory factors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047869
Enrollment
Unknown
Registered
2021-06-27
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative gastrointestinal dysfunction

Interventions

Acupuncture group:Acupoint selection: Zusanli, Shangjuxu, Xuehai
Control group:Routine care

Sponsors

PLA Rocket Force Characteristic Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Patients who are hospitalized for laparoscopic rectal tumor resection and meet the diagnostic criteria; 2. The general condition before surgery is OK, and there is no obvious abnormality in liver, kidney, heart and lung functions; 3. The patient can communicate normally, and there is no obvious contraindication to acupuncture; 4. The skin of the limbs is intact, suitable for acupuncture; 5. Patients in the age range of 18-70 years old, regardless of gender.

Exclusion criteria

Exclusion criteria: 1. Patients with gastrointestinal motility dysfunction due to other reasons before surgery; 2. Mental patients; 3. Pregnancy and lactation patients; 4. Those who have used drugs to promote gastrointestinal motility after surgery, domperidone, mosapride, cisapride; 5. There is damage or infection at the acupuncture point; 6. Those who have participated in other clinical trials at present, or those who have participated in other clinical trials for less than one month.

Design outcomes

Primary

MeasureTime frame
Basic information;Time to first flatus;Time to first bowel movement;Bloating condition;Abdominal pain;Serum motilin;Serum gastrin;a7nicotinic acetylcholine receptor;Tumor necrosis factor-a;interleukin-1;interleukin-6;

Countries

China

Contacts

Public ContactGuan Ling

Chinese People's Liberation Army General Hospital

guanling301@sina.com+86 13520575830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026