Efficacy and safety of duodenal papilla remodeling in the prevention of complications related to duodenal-biliary reflux after ERCP

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047822

Enrollment

Unknown

Registered

2021-06-27

Start date

2021-06-28

Completion date

Unknown

Last updated

2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Repair of duodenal papilla injury

Interventions

Experimental group :duodenal papilla remodeling

Control group:No

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.18-85 years old; 2. Sign preoperative informed consent; 3. Those who underwent EST incision during ERCP lithotomy.

Exclusion criteria

Exclusion criteria: 1. Postoperative choledochal duodenal fistula, particular papilla, Billroth II or Roux-en-Y reconstruction; 2. Coagulation dysfunction or being treated with anticoagulation; 3. Benign or malignant biliary stricture; 4. Patients with intrahepatic bile duct stones.

Design outcomes

Primary

Measure	Time frame
The patient presented abdominal pain, fever, jaundice and other symptoms after surgery, as well as recurrence of cholangitis and bile duct stones;	—

Secondary

Measure	Time frame
Duodenal manometry was performed before and immediately after incision and 1 year after operation;The enterobiliary reflux of the two groups was measured by oral nuclide method 1 week and 1 year after operation;	—

Countries

China

Contacts

Public ContactChai Ningli

Chinese PLA General Hospital

1637424494@qq.com+86 15011362982

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026