Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of cerebral hemorrhage or cerebral infarction; 2. Aged 18 to 65 years; 3. The vital signs are stable, and the onset time is within 12 months; 4.mRS grade 3-5; 5. Can complete the active treadmill action; 6. Cooperation degree S5Q>=3 points, able to understand and actively participate in assessment and training programs; 7. Patients or their families signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Progressive stroke; acute phase of stroke; transient ischemic attack; patients with a history of brain trauma, encephalitis, tuberculous meningitis and other brain parenchyma and central nervous system involvement; 2. Acute coronary syndrome, decompensated heart failure, uncontrolled severe arrhythmia (rapid atrial fibrillation, atrial flutter, paroxysmal ventricular tachycardia, etc.) or high-grade atrioventricular block, severe heart valve disease, hypertrophic Obstructive cardiomyopathy, active myocarditis, pericarditis and other serious heart diseases; 3. Patients with severe hepatic and renal insufficiency, including glomerular filtration rate GFR=200U/L, or aspartate aminotransferase AST>=200U/L; 4. Patients with other serious diseases, such as malignant tumors, end-stage chronic kidney disease, mental disorders, severe malnutrition, etc.; 5. Those with unhealed lower extremity fractures and severe osteoporosis; those with high muscle tension and Ashworth grade 2-4; 6. Untreated deep vein thrombosis of lower extremities; 7. Pregnant or lactating women; 8. Participated in other clinical trials of drugs or medical devices during the same period; 9. The MMSE scale of patients with cognitive impairment is less than or equal to 17 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peak oxygen uptake;Anaerobic threshold (AT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory exchange ratio (RER);Heart rate reserve (HRR);Stroke volume (SV);Cardiac output (CO);ST-T section;rating of perceived exertion (RPE); | — |
Countries
China
Contacts
The First Affiliated Hospital of Shenzhen University