Red horse azole shimron and midazolam in AECOPD patients with mechanical ventilation calm treatment efficacy and safety of comparison

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047775

Enrollment

Unknown

Registered

2021-06-26

Start date

2021-07-01

Completion date

Unknown

Last updated

2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

Experimental group1:RZ calm

Experimental group2:midazolam clam

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 75 years; 2.Estimated duration of mechanical ventilation >=24 hours.

Exclusion criteria

Exclusion criteria: 1.Presence of severe chronic liver disease (Child-Pugh Class B or c) ; 2.Presence of chronic kidney failure; 3.Presence of neurological disorder; 4.Patients with drug dependence, alcohol dependence, mental illness, and cognitive impairment; 5.Pregnant women; 6.Patients with an allergy to Remazolam.

Design outcomes

Primary

Measure	Time frame
Sedation score;Confusion assessment sheet for Intensive Care Unit patients;	—

Secondary

Measure	Time frame
heart rates;Blood pressure;Blood lactic acid;Peak Airway pressure;Airway plateau pressure;Suction frequency;Liver and kidney function;	—

Countries

China

Contacts

Public ContactLi Yong

Cangzhou city central hospital

ly13333367871@hotmail.com+86 13333367871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026