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A volunteer study on the diffusion of local anaesthetic and analgesic effect in two kinds of anterior quadratus lumborum blocks

A volunteer study on the diffusion of local anaesthetic and analgesic effect in two kinds of anterior quadratus lumborum blocks

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047771
Enrollment
Unknown
Registered
2021-06-26
Start date
2021-07-15
Completion date
Unknown
Last updated
2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

quadratus lumbostrum muscle block

Interventions

Experimental group1:anterior quadratus lumborum block in Sagittal plane
Experimental group2:subcostal anterior quadratus lumborum block

Sponsors

Department of Anesthesia and Perioperative Medicine, He'nan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Volunteers fully understand the purpose, nature, method and possible adverse reactions of the experiment, volunteer to serve as volunteers, and sign the informed consent before the start of the experiment; 2. Healthy male and female volunteers aged 18 to 45 years; 3. Male body weight >=50.0kg, female body weight >=45.0kg;Body mass index (BMI) in the range of 19.0 to 26.0kg/m2 (including the critical value); 4. The volunteers had no history of chronic diseases or serious diseases within three years, and were in good general health; 5. Be able to communicate well with researchers, and understand and abide by the requirements of this research.

Exclusion criteria

Exclusion criteria: 1. Anatomic deformity of the thoracic or lumbar spine (as determined by medical history or physical examination), surgical history of the thoracic or lumbar spine or adjacent muscles; 2. Allergic constitution, such as known allergy to the drugs needed in this test (consultation); 3. Patients with contraindications to magnetic resonance (for consultation); 4. Long-term use of painkillers; 5. Patients with coagulation disorders or receiving anticoagulant therapy; 6. Those who refused to participate in the experiment.

Design outcomes

Primary

MeasureTime frame
Two methods of lumbar quadratus block into the way the spread of local anesthetics on magnetic resonance imaging;The range and duration of block of quadratus lumbousus block by two approaches;

Secondary

MeasureTime frame
Operation time required for quadratus lumbosus block by two approaches;

Countries

China

Contacts

Public ContactCui Mingzhu

He'nan Provincial people's Hospital

cuimingzhu78@163.com+86 18639006993

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026