ketamine cystitis
Conditions
Interventions
group 1:Transurethral detrusotomy for autologous bladder enlargement combined with hyaluronic acid bladder instillation
group 2:Transurethral detrusotomy for autogenous bladder enlargement
Sponsors
Department of Urology, Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The previous history of ketamine use; 2.Ineffective conservative treatment such as M receptor antagonists, analgesics,a receptor agonists, and introvesical hyaluronic acid therapy; 3.Ineffective treatment of bladder hydrodistention or recurrence after BH. 4.Intolerant or unwilling to undergo urinary reconstruction surgery; 5.Bladder contracture due to ketamine; 6.Refractory recurrent ketamine cystitis with lower urinary tract symptoms (frequent urination, acute urination, difficulty in urination), pelvic pain, hematuria, etc.
Exclusion criteria
Exclusion criteria: 1. Bladder tumor; 2. Can not tolerate lithotomy position; 3. There is severe cardiopulmonary insufficiency and cannot tolerate surgery; 4. Poor compliance refuses periodic follow-up and signs treatment consent and research informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| maximum bladder capacity;renal function;Compliance;maximum detrusor pressure;maximum urinary flow rate;systematic score;perioperative outcomes;characteristics; | — |
Countries
China
Contacts
Public ContactTang Zhengyan
Xiangya Hospital of Central South University
Outcome results
None listed