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Effects of single femoral nerve block and continuous femoral nerve block on perioperative analgesia and muscle strength in elderly patients undergoing knee replacement

Effects of single femoral nerve block and continuous femoral nerve block on perioperative analgesia and muscle strength in elderly patients undergoing knee replacement

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047747
Enrollment
Unknown
Registered
2021-06-26
Start date
2021-06-22
Completion date
Unknown
Last updated
2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperation pain

Interventions

Experimental group:0.2% ropivacaine 50ml femoral nerve block
control group :0.5% ropivacaine 20ml femoral nerve block +0.2% ropivacaine continuous femoral nerve

Sponsors

Beijing Jishuitan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged > 65 years old; 2. For patients receiving knee surgery under spinal anesthesia, the operation time <=3h.

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in this study; 2. Failure in spinal anesthesia; 3. Preoperative schizophrenia, epilepsy, Parkinson's disease, myasthenia gravis; 4. Inability to communicate with each other due to coma, severe dementia or speech impairment; 5. Craniocerebral injury or neurosurgery; 6. Preoperative LVEF<30%, or patients with sick sinus node syndrome, severe sinus bradycardia (heart rate <50 beats/min), degree ii or above atrioventricular block without pacemaker implantation; 7. Severe liver dysfunction (Child-Pugh Grade C); 8. Severe renal dysfunction (preoperative dialysis); 9. ASA grade IV patients or expected survival <=24 hours; 10. There were skin rupture, infection, vasculitis and local surgical operation requirements in the inguinal area

Design outcomes

Primary

MeasureTime frame
postoperative pain score;

Secondary

MeasureTime frame
Postoperative muscle strength of lower limbs;the time of femoral nerve block;

Countries

China

Contacts

Public ContactTao Yan

Beijing Jishuitan Hospital

taoyan412@163.com+86 17710190412

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026