Intractable epilepsy
Conditions
Interventions
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
6 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 6 to 45 years; 2. Those with good compliance and could complete postoperative follow-up; 3. Those who did not participate in other clinical trials within three months; 4. Generalized or multifocal epilepsy, or no definite localized epileptogenic focus; 5. Those who have seizures more than 3 times (including 3 times) in 3 months and have seizures more than once per month; 6. Under the guidance of neurologist,those were treated with regular antiepileptic drugs, but failed to effectively control the seizure, and were diagnosed as drug refractory epilepsy (patients who could not be completely controlled by drugs and were not suitable for craniotomy); 7. Those who voluntarily participate in the trial and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who refuse to participate in the trial or sign written informed consent; 2. Women in lactation, pregnancy or preparation for pregnancy; 3. Those with a history of vagotomy in the left neck; 4. Those with progressive neurological or systemic diseases; 5. Patients with arrhythmia, asthma or active lung disease and peptic ulcer; 6. Patients with insulin-dependent diabetes; 7. Patients with sleep apnea syndrome; 8. Patients who are undergoing or are expected to receive strong electromagnetic treatment or examination in the observation period; 9. Patients who have participated in other clinical trials within three months; 10. Other situations that researchers and medical staff think are not suitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness, >=50%seizure reduction;Safety evaluation; | — |
Countries
China
Contacts
Public ContactYuping Wang
Xuanwu Hospital Capital Medical University
Outcome results
None listed