Idiopathic Orbital Myositis
Conditions
Interventions
Myositis:Metagenomic sequencing
Control:Metagenomic sequencing
Sponsors
Fudan Eye & ENT Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: idiopathic orbital myositis within 2 months of onset; The patient typically presents with acute onset, painful diplopia, and enhancing fusiform enlargement of the muscle belly, often with involvement of the muscle tendon on CT or MRI scan
Exclusion criteria
Exclusion criteria: bilateral involvement; thyroid-associated ophthalmopathy; definite or probable IgG4-related ophthalmic diseases; cranial nerve III, IV, or VI palsy; Brown syndrome; Duane retraction syndrome; extraocular muscle tumors such as fibroma, lymphoma, and granulosa cell tumor; systemic inflammatory disease; systemic autoimmune disease; positive myositis-specific autoantibodies; paraneoplastic syndrome; drug reaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metagenomic sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metatranscriptomic sequencing; | — |
Countries
China
Contacts
Public ContactJiang Qian
Fudan Eye & ENT Hospital
Outcome results
None listed