polycystic kidney
Conditions
Interventions
case vs control groups:No
Sponsors
Department of Pediatrics, Chinese People's Liberation Army General Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Meet the main diagnostic criteria for polycystic kidney disease: (1) Multiple fluid cysts in the kidneys; (2) Clear family history. 2. Meet the secondary criteria for polycystic kidney disease: (1) Polycystic liver; (2) Renal insufficiency; (3) abdominal wall hernia; (4) Abnormal heart valve; (5) pancreatic cyst; (6) Brain aneurysm; (7) Seminal vesicle cyst.
Exclusion criteria
Exclusion criteria: 1. Medullary cystic nephropathy, the main pathogenic genes are MUC1 and umod; 2. The main pathogenic genes of tuberous sclerosis were TSC1 and TSC2; 3. Von Hippel Lindau disease was mainly caused by VHL; 4. The main pathogenic gene is nphp1 / 2 / 3 / 4; 5. It is caused by other diseases: the end-stage of kidney disease, such as patients receiving long-term hemodialysis treatment, may also have multiple renal cysts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic Testing; | — |
Countries
China
Contacts
Public ContactHua Shaodong
Department of Pediatrics, Chinese People's Liberation Army General Hospital
Outcome results
None listed