Primary Aldosteronism
Conditions
Interventions
SAAE Group:super selective adrenal artery embolization
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Primary aldosteronism was diagnosed in accordance with the 2016 international society of Endocrinology clinical guidelines; 2. Aged 18-75 years males and females; 3. At least 3 non ambulatory office BP >=140 / 90 mmHg while not taking antihypertensive medication or if either the 24-h ambulatory BP average throughout the day is > 130 / 80 mmHg or the daytime average BP is > 135 / 85 mmHg; 4. Patients with a diagnosis of aldosteronoma and / or idiopathic aldosteronism; 5. All current treatments for primary aldosteronism were described in detail to patients and families, who consented to treatment with super selective adrenal artery embolization.
Exclusion criteria
Exclusion criteria: 1. Adenomas greater than 2 cm in diameter; 2. History of stroke, myocardial infarction and endovascular stent placement within 3 months; 3. Renal insufficiency with blood creatinine > 176µMol / L or an estimated glomerular filtration rate < 45 ml / min / 1.73 m2; 4. Concomitant with other severe organic disease such that the patient was unable to tolerate SAAE treatment; 5. Maternal; 6. History of severe contrast allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Home blood pressure;ambulatory blood pressure monitoring;Blood potassium concentration;Plasma aldosterone concentration;Plasma renin activity;Type of antihypertensive drugs;Plain or enhanced CT scan of adrenal gland;Adverse events; | — |
Countries
China
Contacts
Public ContactYi-Fei Dong
Outcome results
None listed