Constipation during pregnancy
Conditions
Interventions
Sponsors
West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 20 to 40 years and the gestational age ranged from 16 to 32 weeks (including the cut-off value); 2. According to Rome IV diagnostic criteria for constipation, patients with functional constipation were diagnosed; 3. The duration of constipation after pregnancy was more than 1 month; 4. The patients participated voluntarily and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. There are intestinal organic diseases, such as inflammatory bowel disease, megacolon, intestinal obstruction, anorectal lesions, etc; 2. Those with occult blood in stool or anemia in pregnancy may affect the evaluation of the test; 3. Patients with severe cardiovascular, respiratory, kidney, blood, endocrine, nervous and mental diseases were considered to affect the evaluator; 4. History of allergy to Bifidobacterium Tetravaccine tablets or similar probiotics; 5. Those who have taken probiotics and other probiotics or laxatives within 2 weeks before taking the study drug; 6. Dysphagia, unable to take medicine on time; 7. Other patients considered unsuitable by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of spontaneous defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of first spontaneous defecation;Evaluation of overall therapeutic effect;Score of symptom Checklist-90 in patients with constipation;Frequency of using emergency medicine Kaiselu; | — |
Countries
China
Contacts
Public ContactZhou Le
West China Second Hospital of Sichuan University
Outcome results
None listed