Acute ischemic stroke
Conditions
Interventions
The experimental group:Endovascular therapy +Xingnaojing injection 20ml, bid, 10 days
The control group:Endovascular therapy
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Patients over 18 years old; 2. Acute ischemic stroke was diagnosed; 3. MRA or CTA showed occlusion of anterior circulation arteries; 4. Acute intravascular therapy (including simple intravascular therapy and bridging therapy) within 24 hours of onset; 5. Randomization was completed within 24 hours after operation; 6. ICF should be signed by patients or family members.
Exclusion criteria
Exclusion criteria: 1. Treated with Xingnaojing injection; 2. Patients with transient ischemic attack; 3. Patients with cerebral hemorrhage on imaging examination; 4. Patients with vasculitis; 5. ALT, AST >= 3 times of the upper limit of normal value, Cr >= 2 times of the upper limit of normal value; 6. Patients with a tendency of bleeding, and severe bleeding occurred within 3 months; 7. Allergic to Xingnaojing, ethanol, glycerin, or allergic constitution; 8. Patients with pregnancy planning, pregnancy, or lactation; 9. Patients with severe heart, liver, kidney disease or malignant tumor, life expectancy < 3 months 10. Patients participating in other drug clinical studies; 11. The patients who are not suitable for the clinical study (such as those with mental and mental disorders, etc.) are considered by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurological prognosis; | — |
Countries
China
Contacts
Public ContactLiu Liping
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed