Transcranial Direct-Current stimulation to improve auditory hallucination in schizophrenia and explore the electrophysiological mechanism : A Randomized controlled study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047636

Enrollment

Unknown

Registered

2021-06-21

Start date

2021-06-21

Completion date

Unknown

Last updated

2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

The experimental group:Received transcranial direct current stimulation

The control group:Received pseudo stimulation

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Diagnostic criteria of schizophrenia in the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition); 2. Age 18-50 years old; 3. The dose of antipsychotics was stable in the last 3 months; 4. All patients showed refractory auditory hallucinations, defined as persistent daily hallucinations without remission for at least 3 months despite antipsychotic medication. All patients remained on medication throughout the study period.

Exclusion criteria

Exclusion criteria: 1. During pregnancy and lactation; 2. Prior MECT treatment within 6 months; 3. Substance dependence or other psychiatric comorbidities; 4. Organic brain diseases; 5. Serious physical diseases such as heart disease; 6. Pacemaker; 7. Comorbid epilepsy; 8. Hearing impairment.

Design outcomes

Primary

Measure	Time frame
Auditory;Psychopathological level;Cognitive function;	—

Countries

China

Contacts

Public ContactChen Dachun

Beijing Huilongguan Hospital

cdc1963@sina.com+86 13520506068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026