Bladder carcinoma
Conditions
Interventions
Case group:Nil
Sponsors
Xiangya Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patients with muscle invasive bladder cancer diagnosed by pathology department of our hospital; 2. Clinical stage t2-t4an0 / xm0; 3. Clinicians evaluate the patients suitable for radical cystectomy; 4. Karnofsky score >=70; 5. Patients over 18 years old; 6. Laboratory indexes: absolute neutrophil count (ANC) >=1000/mm3, platelet count >=100000/mm3, hemoglobin >=9.0g/dl, bilirubin =60mL/min/1.73m2.
Exclusion criteria
Exclusion criteria: 1. Patients who have previously received radiotherapy, immunotherapy and other adjuvant treatment of tumor; 2. Patients with serious heart disease (i.e. grade III and above heart function); 3. Patients with serious medical or mental diseases, including severe active infection; 4. Patients who received other surgical treatment 4 weeks ago; 5. The following symptoms occurred within 6 months: myocardial infarction, severe/unstable angina, coronary artery / peripheral artery bypass, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack; 6. Patients with sustained arrhythmia >=2 (NCI CTCAE version 4.0 grade)(The attachment 2); 7. Patients with diseases or infections related to human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS); 8. Patients who participated in other clinical trials at the same time; 9. Pregnant or lactating women; 10. Patients with alcohol or narcotic drug abuse, drug use history, or mental history (such as schizophrenia, obsessive-compulsive disorder, depression), who have antagonistic personalities, bad motivation, paranoia, or other emotional or intellectual problems that may affect the informed effectiveness of the study; 11. Patients who are unable to cooperate with the relevant examination of the project and do not agree to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological stage;Abdominal computed tomography; | — |
Countries
China
Contacts
Public ContactZu Xiongbing
Xiangya Hospital
Outcome results
None listed