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To explore the correlation between HRCT imaging features and grading of bronchial asthma patients — a cohort study

To explore the correlation between HRCT imaging features and grading of bronchial asthma patients — a cohort study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047624
Enrollment
Unknown
Registered
2021-06-21
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchial asthma

Interventions

case series:None

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-79 years (including 18 and 79 years old), gender and race are not limited; 2. Diagnostic criteria (those who meet items 1-4 or 4 and 5 can be diagnosed as asthma): (1) Repeated episodes of wheezing, shortness of breath, chest tightness or coughing are mostly related to exposure to allergens, cold air, physical and chemical stimuli, viral upper respiratory tract infections, exercise, etc.; (2) At the time of the attack, scattered or diffuse wheezing can be heard in both lungs, mainly in the expiratory phase, and the expiratory phase is prolonged; (3) The above symptoms and signs can be relieved by treatment or by themselves; (4) Excluding wheezing, shortness of breath, chest tightness and cough caused by other diseases; (5) Those with atypical clinical manifestations (such as no obvious wheezing or signs) should have at least one of the following positive tests: 1) Positive bronchial provocation test or exercise provocation test; 2) The positive FEV1 increase of bronchodilation test is >=12%, and the absolute value of FEV1 increase is >=200ml; 3) The intraday (or 2-week) variation rate of peak expiratory flow (PEF) is >=20%.

Exclusion criteria

Exclusion criteria: 1. The required information is incomplete; 2. The patient has other respiratory diseases other than COPD, such as COPD, interstitial pneumonia, active pulmonary tuberculosis, community-acquired pneumonia, lung cancer, bronchiectasis, cor pulmonale, pulmonary embolism, etc.; 3. Alcoholism or narcotic drug abuse, history of drug use, or a history of mental illness (such as schizophrenia, obsessive-compulsive disorder, depression), confrontation of character, bad motivation, paranoia, or other emotional or intellectual problems that may affect the informed validity of participation in this research; 4. Participating in other drug clinical trial projects, or stopping for less than 3 months; 5. Patients who cannot cooperate with the relevant examinations of this project and do not agree to sign the informed consent form.

Design outcomes

Secondary

MeasureTime frame
pulmonary function examination;

Countries

China

Contacts

Public ContactChen Xiaodong
45994381@qq.com+86 18825135867

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026