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Effect of different doses of butorphanol on half effective concentration of propofol in hysteroscopy

Effect of different doses of butorphanol on half effective concentration of propofol in hysteroscopy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047622
Enrollment
Unknown
Registered
2021-06-21
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control group:None
Group A:10ug/kg butorphanol
Group B:15ug/kg butorphanol
Group C:20ug/kg butorphanol

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Informed consent for surgery and anesthesia has been obtained from patients and their families; 2. Age: 18-60 years old; 3. BMI 18-30kg/m^2; 4. ASA classification I-II; 5. The disease types are endometrial polyps, cervical polyps, uterine fibroids, and endometrial lesions; 6. The preoperative airway evaluation was normal (Mallampati I-II grade, mouth opening > 3 cm, nail-mind distance > 6 cm, normal head and neck mobility, no cervical spondylosis and sleep apnea syndrome).

Exclusion criteria

Exclusion criteria: 1. Combined with obvious heart, lung, liver, kidney and nervous system diseases; 2. History of mental illness; 3. Long-term use of sedative and analgesic drugs, alcohol dependence and drug addiction; 4. Preoperative systolic blood pressure >= 160mmHg, diastolic blood pressure >= 110mmHg, heart rate >= 110bpm; 5. Those who are allergic to experimental drugs; 6. Received general anesthesia surgery within 3 months.

Design outcomes

Primary

MeasureTime frame
body response;

Secondary

MeasureTime frame
systolic blood pressure;heart rate;blood oxygen saturation;respiratory rate;pain visual analogue scale;alertness/sedation index;

Countries

China

Contacts

Public ContactWang Fangjun
wfjlxy006@126.com+86 13458253172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026