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Low-frequency repetitive transcranial magnetic stimulation improves cognitive flexibility and brain function in patients with insomnia

Low-frequency repetitive transcranial magnetic stimulation improves cognitive flexibility and brain function in patients with insomnia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047603
Enrollment
Unknown
Registered
2021-06-20
Start date
2021-06-17
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary insomnia

Interventions

Group 1:left dorsolateral prefrontal transcranial magnetic stimulation
Group 2:left dorsolateral prefrontal pseudostimulation
Group 3:none

Sponsors

Jiangsu Shengze Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for insomnia in DSM-5; 2. Benzodiazepine patients must meet the diagnostic criteria for mental and behavioral disorders induced by sedatives and hypnotics in ICD-10, non-benzodiazepine patients should not meet the diagnostic criteria for mental and behavioral disorders induced by sedatives and hypnotics in ICD-10; 3. Agree and voluntarily participate in the experiment; 4. Junior high school education level or above; 5. Possess certain cognitive ability; 6. Aged 18 to 65 years.

Exclusion criteria

Exclusion criteria: 1. There are contraindications for transcranial magnetic resonance (TMS) treatment and magnetic resonance imaging (MRI) examination, such as head trauma, history of epilepsy, and metal implants in the body; 2. Suffering from other mental illnesses (including drug-induced mental illnesses); 3. Serious physical disease or major organ disease; 4. With sleep deprivation; 5. Pregnancy status.

Design outcomes

Primary

MeasureTime frame
Cognitive-behavioral task indicators;

Secondary

MeasureTime frame
PSQI score;Electroencephalogram;Brain-derived nerve growth factor;

Countries

China

Contacts

Public ContactHe Chuan

Jiangsu Shengze Hospital

he-chuan@outlook.com+86 13962106994

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026