Chronic cough
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Be able to provide written informed consent (signature); 2. Adults (aged >= 18 years); 3. Cough duration > 8 weeks; 4. No obvious abnormality on chest X-ray or CT.
Exclusion criteria
Exclusion criteria: 1. Respiratory tract infection 8 weeks before the initial screening; 2. Smoking now, less than half a year after quitting smoking, and more than 20 pack years of smoking; 3. Be taking ACEI; 4. Cardiopulmonary function, liver and kidney function impairment, tumors, infectious diseases; 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin prick test;Fractional exhaled nitric oxide;Pulmonary function + bronchial challenge test;CT;24-hour esophageal pH impedance; | — |
Countries
China
Contacts
West China Hospital, Sichuan University