Gitelman syndrome
Conditions
Interventions
control group:Normal saline injection + conventional treatment group
intervention group:Regular injection of umbilical cord MSCs + conventional treatment group
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate and sign the informed consent; 2. Aged between 18 and 60 years; 3. The diagnosis of Gitelman syndrome was established; 4. No potassium supplementation therapy for at least six months after the diagnosis of Gitelman.
Exclusion criteria
Exclusion criteria: 1. Other reasons such as Gitelman syndrome secondary to drugs; 2. Those who are pregnant, breastfeeding or intend to become pregnant, and women of childbearing age who do not use effective contraceptive measures (referring to intrauterine devices, oral contraceptives and obstruction measures); 3. Patients with severe heart disease, such as: decompensated heart failure (NYHA stage III and IV); unstable angina pectoris; history of myocardial infarction within the past 12 months, etc.; 4. Patients with secondary hyperuricemia caused by blood disease, severe kidney disease or tumor radiotherapy and chemotherapy; 5. Brain disease, abnormal judgment ability; mental illness unable to cooperate; 6. Alcohol or drug addicts; 7. Those who have participated in other clinical trials within three months before the screening of this trial; 8. Malignant tumor, active tuberculosis; 9. Complicated with other diseases, and the researchers believe that it will affect the evaluation of efficacy or poor compliance; 10. Those taking glucocorticoid drugs; 11. White blood cell count < 4.0x10^9/L, or platelet < 100x10^9/L, or hemoglobin <90g/L; 12. For any other reason, the investigator considers it inappropriate to participate in the trial; 13. Those who are allergic to all the drugs in this test or their ingredients, or those who have allergies to existing symptoms, or those with hypersensitivity constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood K+, Mg2+;Urine Ca2+/urine creatinine; | — |
Countries
China
Contacts
Public ContactZhao Jiajun
Shandong Provincial Hospital
Outcome results
None listed