latent autoimmune diabetes in adults
Conditions
Interventions
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 60 years; 2. The diagnosis of latent immune diabetes (LADA) was established (according to the 2012 consensus on diagnosis and treatment of latent autoimmune diabetes in adults (LADA)); 3. Islet autoantibodies are positive, and GAD is the first recommended antibody to be detected; 4. Do not rely on insulin therapy for at least six months after the diagnosis of diabetes.
Exclusion criteria
Exclusion criteria: 1. Those who are pregnant, breastfeeding or intend to become pregnant, women of childbearing age who do not use effective contraceptive measures (referring to intrauterine devices, oral contraceptives and obstruction measures); 2. Patients with severe heart disease, such as: decompensated heart failure (NYHA stage III and IV); unstable angina pectoris; history of myocardial infarction within the past 12 months, etc.; 3. Patients with secondary hyperuricemia caused by blood disease, kidney disease or tumor radiotherapy and chemotherapy; 4. Brain disease, abnormal judgment ability; mental illness unable to cooperate; 5. Alcohol or drug addicts; 6. Those who have participated in other clinical trials within three months before the screening of this trial; 7. Malignant tumor, active tuberculosis; 8. Complicated with other diseases, and the researchers believe that it affects the evaluation of efficacy or poor compliance; 9. Those taking glucocorticoid drugs; 10. White blood cell count < 3.0x10^9/L, or platelets < 100x10^9/L, or hemoglobin < 90g/L; 11. For any other reason, the investigator considers it inappropriate to participate in the trial; 12. Those who are allergic to all the drugs in this test or their ingredients, or have existing allergies, or have hypersensitivity constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood routine;Coagulation;Blood sugar;Islet autoantibodies (GAD, IAA, ICA) titers; | — |
Countries
China
Contacts
Public ContactHou Xu
Shandong Provincial Hospital
Outcome results
None listed