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A randomized, double-blind, placebo-controlled trial for Xinguan Fuzheng Zhuanyin Decoction to reduce the viral load of the delta variant of COVID-19

A randomized, double-blind, placebo-controlled trial for Xinguan Fuzheng Zhuanyin Decoction to reduce the viral load of the delta variant of COVID-19

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047596
Enrollment
Unknown
Registered
2021-06-20
Start date
2021-06-18
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for COVID-19 (National Eighth Edition); 2. Aged over 18 years; 3. Normal body temperature within 48 hours; 4. In the case of inhaling air, SpO2 > 93%; 5. The onset time is more than 7 days; 6. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. The nucleic acid test turns negative twice in a row (24 hours apart); 2. Those who meet the discharge criteria and have a positive nucleic acid after discharge; 3. Severely and critically ill patients (8th edition standard); 4. Abnormal liver and kidney function (more than 2 times the normal value); 5. Allergic to known traditional Chinese medicine; 6. Those who do not cooperate with taking traditional Chinese medicine; 7. Pregnant women.

Design outcomes

Primary

MeasureTime frame
The change of viral load;Prognosis;

Secondary

MeasureTime frame
Nucleic acid negative time;The ratio of nucleic acid to negative;Major symptoms disappeared;CT imaging changes of chest;Hospital stays;The change of tongue and pulse ;

Countries

China

Contacts

Public ContactZhang Zhongde

Guangdong Provincial Hospital of Traditional Chinese Medicine

doctorzzd99@163.com+86 13903076359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026