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A pharmacokinetic study of continuous infusion of ciprofol in elderly patients

A pharmacokinetic study of continuous infusion of ciprofol in elderly patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047580
Enrollment
Unknown
Registered
2021-06-20
Start date
2021-12-18
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:Ciprofol Injection

Sponsors

Zhejiang Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 60 years, and the gender is not limited; 2. American Anesthesiologist Classification (ASA) I-II; 3. For patients who need general anesthesia with endotracheal intubation for elective gastrointestinal tumor surgery, 3h=95% when breathing air; 6. Be able to understand the research process and methods, and voluntarily participate in this research.

Exclusion criteria

Exclusion criteria: 1. Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past; 2. Known or suspected allergies or contraindications to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Combined with severe heart, lung, liver, kidney dysfunction, uncontrolled diabetes or hypertension; 4. Those with a history of mental illness, abuse or long-term use of sedatives and antidepressants; 5. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.

Design outcomes

Primary

MeasureTime frame
BIS value and blood concentration;

Secondary

MeasureTime frame
Incidence of injection pain;Length of stay in PACU;Incidence of postoperative adverse reactions;Hemodynamics;

Countries

China

Contacts

Public ContactLu Man

Zhejiang Provincial Hospital of Traditional Chinese Medicine

174386983@qq.com+86 18368021733

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026