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Application of 16s rDNA sequence analysis in the study of ocular surface microflora in patients with blepharitis of demodex

Application of 16s rDNA sequence analysis in the study of ocular surface microflora in patients with blepharitis of demodex

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047574
Enrollment
Unknown
Registered
2021-06-20
Start date
2021-06-18
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Demodex blepharitis

Interventions

patient group:none
control group:none

Sponsors

Zhejiang Provincial Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for normal persons: (1) Aged over 18 years, no subjective symptoms of eye discomfort, no signs of demodex blepharitis; (2) Voluntarily participate in the research of this topic, and all subjects signed the informed consent. 2. Inclusion criteria for patients with Demodex blepharitis: (1) Aged over 18 years, meeting the diagnostic criteria for Demodex blepharitis; (2) Voluntarily participate in the research of this topic, and all subjects signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who have undergone eye surgery or have other eye diseases such as glaucoma, iritis, etc.; 2. Associated with ocular surface abnormalities such as eyelid insufficiency, active infectious keratitis, herpes simplex keratitis, trigeminal nerve disease and other diseases known to affect corneal nerves; 3. Those who cannot tolerate the sampling or inspection process.

Design outcomes

Primary

MeasureTime frame
ocular surface flora;

Countries

China

Contacts

Public ContactFu Ya'na
1029091739@qq.com+86 13003605152

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026