contrast-induced acute kidney injury
Conditions
Interventions
Experimental group:Intensive hydration treatment regimen
Control group:General hydration regimen
Sponsors
Zhongda Hospital of Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this trial and sign the informed consent; 2. Aged 18 to 85 years; 3. Proposed coronary intervention; 4. AGEF score>1.16; 5. No related contraindications.
Exclusion criteria
Exclusion criteria: 1. There is a history of contrast agent allergy; 2. Lactation, pregnancy; 3. Existing or suspected acute kidney injury; 4. Those who used contrast agents and nephrotoxic drugs within 1 week before enrollment; 5. Severe renal insufficiency requiring hemodialysis; 6. Use of aortic balloon counterpulsation, acute heart failure, liver failure, connective tissue disease, tumor, serious infectious disease, cardiogenic shock in hospital, sudden cardiac death, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast nephropathy incidence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events in postoperative hospitalization;Actual or percent (%) changes in serum creatinine, eGFR, sodium, and brain natriuretic peptide; | — |
Countries
China
Contacts
Public ContactYan Gaoliang
Zhongda Hospital of Southeast University
Outcome results
None listed