FindTrial
Sign In

Comparison of intranasal dexmedetomidine and dexmedetomidine-ketamine combined sedation in preoperative sedation of children with congenital heart disease

Comparison of intranasal dexmedetomidine and dexmedetomidine-ketamine combined sedation in preoperative sedation of children with congenital heart disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047541
Enrollment
Unknown
Registered
2021-06-20
Start date
2021-06-25
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative sedation in children with congenital heart disease

Interventions

Group 1:Dexmedetomidine + Esketamine was administered through the nasal mucosa
Group 2:Dexmedetomidine was administered through the nasal mucosa

Sponsors

Department of Anesthesiology, He'nan Provincial People's Hospital Heart Center-Huazhong Fuwai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: 1.Aged <= 3 years; 2.Intended to perform cardiac surgery under general anesthesia; 3.ASA (II-IV); 4.Parents voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Allergy to the study drug; 2.Abnormal nasal structure; 3.Severe abnormal liver and kidney function; 4.Preoperative bradycardia; 5.Pre-operative use of sedative drugs.

Design outcomes

Primary

MeasureTime frame
Improved vigilance/sedation score;Children's Hospital of Wisconsin Sedation Scale to assess sedation levels;—

Countries

China

Contacts

Public ContactQiu Lin

He'nan Provincial People's Hospital Heart Center - Huazhong Fuwai Cardiovascular Hospital

qiulin2005@163.com+86 13938467818

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026