valvular heart disease
Conditions
Interventions
Control group:Induction of etomidate combined with sufentanil in anesthesia
Experimental group:Induction of etomidate anesthesia combined with esketamine
Sponsors
Center for Anesthesiolosy, Beijing Anzhen Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.American Society of anesthesiologists (ASA): grade II-III; 2.There are indications for operation; 3.The liver and kidney function were normal; 4.The coagulation function was normal; 5.All patients' family members voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Infectious diseases and hematological diseases; 2.Patients with elevated blood lactic acid or metabolic disorder; 3.Patients with active hemorrhage, severe intracranial hypertension, hypertension and acute myocardial infarction; 4.Patients with history of surgical contraindications; 5.History of contraindication to narcotic drugs; 6.Patients with severe infection and dysfunction of important organs (brain, lung, etc.); 7.Unable to cooperate with the investigators due to mental disorder or mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamics;Inflammatory stress response; | — |
Countries
China
Contacts
Public ContactLiu Wenjun
Center for Anesthesiolosy, Beijing Anzhen Hospital
Outcome results
None listed