Study on the relationship between different ventilation modes and postoperative pulmonary complications of esophageal carcinoma

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047470

Enrollment

Unknown

Registered

2021-06-20

Start date

2021-06-15

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications of esophageal cancer

Interventions

Experimental group1:VT-guided ventilation regulated by minimum driving pressure

Experimental group2:PEEP-guided ventilation regulated by minimum driving pressure

Experimental group3:Keep VT at 6 ml/kg and PEEP at 5 cmH2O

Eligibility

Sex/Gender

All

Age

19 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status I or II; 2. Patients aged 19 to 75 years; 3. Surgery for esophageal cancer requiring one-lung ventilation.

Exclusion criteria

Exclusion criteria: 1. History of radiotherapy and chemotherapy; 2. Patients with serious complications such as respiratory failure, pulmonary infection, atelectasis, emphysema, pulmonary heart disease, pleurisy; 3. Taboo patients treated with PEEP: intracranial hypertension, bronchopleural fistula, hypoxic shock, right ventricular failure.

Design outcomes

Primary

Measure	Time frame
Incidence of pulmonary complications;	—

Secondary

Measure	Time frame
Incidence of pulmonary complications;Postoperative extrapulmonary complications;Unplanned admission to ICU or re-hospitalization is required;Hospital mortality;	—

Countries

China

Contacts

Public ContactCao Longhui

Sun Yat-Sen University Cancer Center

caolh@sysucc.org.cn+86 13826092036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026