esketamine
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 20 to 40 years, primipara; 2.ASA <= II level; 3.Pregnancy greater than 28 weeks; 4.Height 150cm-170cm; 5.Weight 50kg-100kg; 6.No serious cardiovascular and cerebrovascular diseases; 7.The parturient can communicate well with the follower; 8.Volunteer to participate in this research and sign the relevant informed consent; 9.Voluntarily accept postoperative intravenous analgesia and plan to undergo cesarean section patients under combined spinal-epidural anesthesia.
Exclusion criteria
Exclusion criteria: 1.Hypertension, diabetes; 2.Allergic to dexmedetomidine and sufentanil; 3.Have a history of cesarean section surgery; 4.Premature rupture of membranes, placenta previa, eclampsia, etc.; 5.Long-term use of sedatives, hypnotics, opioids, and psychotropic drugs; 6.HELLP syndrome; 7.Pregnancy-induced hypertension syndrome; 8.Patients change the method of anesthesia during the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital signs;Analgesia score;Sedation score;Sleep quality;Edinburgh score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions; | — |
Countries
China
Contacts
The First Pepole's Hospital of Huaihua