esophageal cancer
Conditions
Interventions
Gold Standard:Histopathology.
Index test:Esophageal 
cytology, 
Sponsors
The First Affiliated Hospital of Naval Military Medical University (Changhai Hospital of Shanghai)
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Hospital opportunistic screening population aged 40 to 75 years.
Exclusion criteria
Exclusion criteria: 1.Patients have symptoms of dysphagia, hematemesis and melena; 2.Patients have received gastroscopy in the past year; 3.Patients have clear esophageal intraepithelial neoplasia (dysplasia) in the past; 4.Patients with esophagus-gastric varices and esophageal stenosis; 5.Patients have a history of esophageal or gastric surgery; 6.Patients have blood coagulation dysfunction or need to continue taking anticoagulant or antiplatelet drugs; 7.There are contraindications to gastroscopy and mucosal biopsy; 8.The life expectancy of suffering from other serious diseases is less than 5 years; 9.Refused to cooperate with the research plan and sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of cytological screening for the diagnosis of esophageal cancer and esophageal intraepithelial neoplasia (dysplasia); | — |
Secondary
| Measure | Time frame |
|---|---|
| The diagnostic value of DNA quantitative detection in esophageal cancer and esophageal intraepithelial neoplasia;Accuracy of cytological screening in the diagnosis of high-grade esophageal lesions (intraepithelial neoplasia and esophageal cancer);The diagnostic value of cytology combined with DNA quantitative detection for esophageal carcinoma and esophageal intraepithelial neoplasia; | — |
Countries
China
Contacts
Public ContactShu Qing
Shenzhen Second People's Hospital
Outcome results
None listed