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Effect of ear acupoint sticking therapy on gastrin and 5-hydroxytryptamine in patients after total knee arthroplasty

Effect of ear acupoint sticking therapy on gastrin and 5-hydroxytryptamine in patients after total knee arthroplasty

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047397
Enrollment
Unknown
Registered
2021-06-16
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after total knee replacement

Interventions

Sponsors

Guangdong Second Hospital of Traditional Chinese Medicine (Guangdong Institute of Traditional Chinese Medicine Engineering Technology)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who need total knee arthroplasty due to knee osteoarthritis are classified by American Society of anesthesiologists (ASA) grade I-II, and the operation time is expected to be more than 1 hour; 2. Combined lumbar and epidural anesthesia was used, and postoperative intravenous patient-controlled analgesia (PCIA) was performed; 3. The patients voluntarily participated in the study and signed the informed consent; 4. There was no absolute contraindication of auricular plaster therapy.

Exclusion criteria

Exclusion criteria: 1. The patients who had nausea and vomiting 24 hours before operation, chemotherapy within 4 weeks or radiotherapy within 8 weeks, and hormone use within 1 week; 2. There are other diseases that easily affect the observation results, liver and kidney dysfunction, etc.; 3. Patients are not suitable to participate in the experiment; 4. Patients do not cooperate, resulting in intervention measures can not be implemented.

Design outcomes

Primary

MeasureTime frame
5-hydroxytryptamine;Gastrin;The time and frequency of first occurrence of postoperative nausea and vomiting;Severity of postoperative nausea and vomiting;Use of antiemetic drugs;Efficacy evaluation criteria for nausea;

Countries

China

Contacts

Public ContactGuo Meirong

Guangdong Second Hospital of Traditional Chinese Medicine (Guangdong Institute of Traditional Chinese Medicine Engineering Technology)

850962190@qq.com+86 13751839021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026