Functional constipation
Conditions
Interventions
Wheat Peptides Group:serving of wheat peptides 15g twice daily
Placebo Group:serving of placebo 15g twice daily
Sponsors
Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years; 2. Select the Rome III diagnostic criteria for functional constipation as the screening population for functional constipation. Volunteers must show symptoms 6 months before diagnosis and meet the diagnostic criteria in the last 3 months. In addition to the number of bowel movements less than 3 times a week, one or more of the following symptoms must also be included: (1) At least 25% of bowel movements feel laborious; (2) At least 25% of bowel movements are lumpy or hard; (3) At least 25% of defecation have incomplete defecation; (4) At least 25% of bowel movements have a sense of obstruction of the rectum; (5) At least 25% of bowel movements require manual assistance.
Exclusion criteria
Exclusion criteria: 1. Intestinal stress syndrome accompanied by constipation; 2. Sparse stool or watery stool; 3. Surgery within 30 days caused constipation symptoms; 4. Those who have recent difficulty in defecation caused by severe organic diseases (colon cancer, severe enteritis, intestinal obstruction, inflammatory bowel disease, etc.); 5. Those who have had acute gastrointestinal diseases within 30 days; 6. Women during pregnancy and menstruation; 7. Patients with constipation combined with serious systemic diseases such as cardiovascular, liver, kidney and hematopoietic system; 8. Those who have other concomitant diseases being treated; 9. Take items related to the tested function in a short period of time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation intensity;Gut microbiota; | — |
Countries
China
Contacts
Public ContactFeng Fengqin
Zhejiang University
Outcome results
None listed