The effect of deep neuromuscular block combined with low pneumoperitoneum pressure on renal function in elderly patients undergoing robotic laparoscopic radical prostatectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047360

Enrollment

Unknown

Registered

2021-06-12

Start date

2021-06-12

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney injury in elderly patients

Interventions

Group 1:Low pneumoperitoneum pressure + deep neuromuscular block

Group 2:Normal pneumoperitoneum pressure + deep neuromuscular block

Group 3:Normal pneumoperitoneum pressure + moderate neuromuscular block

Eligibility

Sex/Gender

Male

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Elderly patients (65 years old and above), planning to undergo robot-assisted radical resection of prostate cancer (bladder cancer); 2. Renal function is basically normal before operation (creatinine clearance rate>60ml/min); 3. Patients with ASA classification I-III; 4. BMI < 30kg/m^2; 5. Sign the informed consent form voluntarily.

Exclusion criteria

Exclusion criteria: 1. Myasthenia gravis; 2. Patients using hormones within the past 3 months; 3. The researcher believes that it is not suitable to participate in this research; 4. Patients who are participating in other clinical trials.

Design outcomes

Primary

Measure	Time frame
Creatinine clearance;Creatinine;Urea nitrogen;	—

Secondary

Measure	Time frame
Blood neutrophil gelatinase-associated lipocalin;	—

Countries

China

Contacts

Public ContactXu Junmei

The Second Xiangya Hospital of Central South University

13975148864@139.com+86 13975148864

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026