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Determination ED50 and ED95 of cyclopofol in colonoscopy

ED50 and ED95 of cyclopofol used in gastrointestinal endoscopy and comparison with equivalent propofol

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047354
Enrollment
Unknown
Registered
2021-06-12
Start date
2021-07-10
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal disorders

Interventions

Group 1:Give different doses of cyclopofol
Propofol group:Propofol
Cycloprofol group:Cycloprofol

Sponsors

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. ASA I-II level patients who intend to undergo painless gastrointestinal endoscopy in the Sir Run Run Shaw Hospital, Zhejiang University School of Medicine; 2. The liver function, cardiopulmonary function, blood coagulation function, chest X-ray and electrocardiogram were basically normal before operation; 3. Aged >= 65 years; 4. Volunteer to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. 18.5<= BMI<= 28; 2. Long-term history of allergy to opioids and fat emulsions; 3. History of gastrointestinal surgery; 4. Contraindications for sedation or general anesthesia; 5. Vulnerable groups, including people with mental illness, critically ill patients, pregnant women, minors, cognitive impairment, etc.

Design outcomes

Primary

MeasureTime frame
Dosage of cyclopofol;Incidence of injection pain;

Countries

China

Contacts

Public ContactMa Xiaoxu
Maxiaoxu2008@163.com+86 13757164869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026