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Clinical study of intravitreal injection of conbercept in preventing postoperative complications of vitrectomy for diabetic retinopathy

Clinical study of intravitreal injection of conbercept in preventing postoperative complications of vitrectomy for diabetic retinopathy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047351
Enrollment
Unknown
Registered
2021-06-12
Start date
2021-06-15
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic retinopathy

Interventions

Group A:Intravitreal injection of conbercept was performed 2 weeks after operation
Group B:No intravitreal injection of conbercept was performed

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Stage 4-6 diabetic retinopathy; 2. Need to undergo vitrectomy surgery.

Exclusion criteria

Exclusion criteria: 1. Intraocular injection (anti-VEGF drugs) was performed within 3 months before joining the group; 2. Have performed complete pan-retinal photocoagulation laser treatment; 3. Optic nerve injury, endophthalmitis, primary disease (glaucoma, etc.); 4. Patients with diabetic retinopathy in the degenerative stage of the reproductive membrane.

Design outcomes

Primary

MeasureTime frame
Incidence of vitreous hemorrhage;Incidence of diabetic macular edema;Incidence of neovascular glaucoma;

Secondary

MeasureTime frame
Best corrected visual acuity;Intraocular pressure;Silicone oil was removed 12 months after operation;The number of operations for retinal detachment and PPV within 12 months;Intraocular VEGF level;

Countries

China

Contacts

Public ContactChen Huijin
chjdoc@alimail.com+86 13641103935

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026