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Study on the mechanism and clinical value of HNF4? regulating hsa-miR-487b/ZMYND8 axis in liver fibrosis

Study on the mechanism and clinical value of HNF4? regulating hsa-miR-487b/ZMYND8 axis in liver fibrosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047338
Enrollment
Unknown
Registered
2021-06-12
Start date
2022-09-01
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Fibrosis

Interventions

Liver Fibrosis group:Nil
Healthy control group:Nil

Sponsors

The Second Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. All cases underwent liver biopsy or required surgical removal of liver tissue, and had a corresponding pathological diagnosis; 2. Aged >= 18 years; 3. The enrolled cases are registered with detailed clinical data such as age, gender, AST, ALT, TBIL, history of drinking, etc.

Exclusion criteria

Exclusion criteria: 1. The patient and family members do not agree to participate in sample collection and provide necessary medical history; 2. There is a serious uncontrollable infection; 3. A history of severe gastrointestinal disease, abnormal renal function, history of heart disease and other organs; 4. The patient currently has other organ diseases that may affect the evaluation of this study; 5. Tumors in any part including the liver; 6. Patients with systemic immune system diseases.

Design outcomes

Primary

MeasureTime frame
the miRNA of hsa-miR-487b;

Countries

China

Contacts

Public ContactXu Yiheng

The Second Affiliated Hospital of Kunming Medical University

29009312@qq.com+86 18987675404

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026