Study on the effect of transcranial direct current stimulation on pain regulation

The effect of high-definition transcranial direct current stimulation on pain processing in healthy adults: a single-blind crossover controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047330

Enrollment

Unknown

Registered

2021-06-12

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Group 1:A: M1-tDCS

B:DLPFC-tDCS

C: sham stimulation

Group 2: B:DLPFC-tDCS

A: M1-tDCS.

Grup 3: C: sham stimulation

A: M1-tDCS

B:DLPFC-tDCS.

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Right-handed, painless healthy people aged 18 to 40 years; 2. No clinically significant or unstable medical, neuropsychiatric, or chronic pain disorders; 3. No history of drug abuse or dependence; 4. No central nervous system effective drugs; 5. No brain surgery History, tumor history, history of intracranial metal implantation.

Exclusion criteria

Exclusion criteria: 1. Subjects with hand disease and underlying neuropathy such as diabetes and chronic pain; 2. Subjects with documented transcranial direct current stimulation contraindications such as implanted medical equipment or history of epilepsy; 3. Subjects with chronic pain and neurological or mental illness; 4. Subjects who have received analgesic medications in the past 24 hours.

Design outcomes

Primary

Measure	Time frame
Conditioned pain modulatory;	—

Countries

China

Contacts

Public ContactWang Yuling

The Sixth Affiliated Hospital of Sun Yat-Sen Universitythe six affiliated hospital of sun yat-sen university

wangyul@mail.sysu.edu.cn+86 13054445587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026