Systemic lupus erythematosus
Conditions
Interventions
case series:Nil
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: Retrospective research: 1. Aged 14 to 65 years old, regardless of gender or ethnicity; 2. Diagnosed as systemic lupus erythematosus: according to the 2009 ACR/EULAR classification and diagnosis criteria for SLE; 3. All patients were tested for anti-phospholipid antibodies, including aCL, LA, and anti-ß2GP1; Prospective research: 1. Aged 14 to 65 years old, regardless of gender or ethnicity; 2. Diagnosed as systemic lupus erythematosus: according to the 2009 ACR/EULAR classification and diagnosis criteria for SLE; 3. Enrollment at baseline did not suffer from kidney injury (diagnostic criteria for lupus nephritis: 24-hour urine protein quantitative >= 0.5g/24h or confirmed by renal biopsy as lupus nephritis); 4. All patients were tested for anti-phospholipid antibodies, including aCL, LA, and anti-ß2GP1; 5. Sign the written consent, patients under the age of 18 need to have a legal guardian to sign an informed consent form at the same time.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant tumors; 2. eGFR< 30 ml/min/1.73m2 (calculated using CKD EPI formula); 3. Severe active central nervous system (CNS) lupus (including epilepsy, psychosis, organic brain Syndrome, cerebrovascular accident, encephalitis or central nervous system vasculitis); 4. The patient has acute or chronic infection that needs treatment, and the investigator judges it is not suitable for inclusion in the study; 5. Pregnancy, breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urine protein quantification; | — |
Countries
China
Contacts
Public ContactWang Meiying
Shenzhen Second People's Hospital
Outcome results
None listed