Induced abortion
Conditions
Interventions
A:Fentanyl + propofol
B:Esketamine + propofol
C:Fentanyl + Remazolam
D:Esketamine + Remazolam
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 45 years; 2. ASA grade: I- II; 3. BMI: 18-28 kg /m2; 4. Patients receiving painless abortion in the outpatient department; 5. Clearly understand and voluntarily participate in the study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with obvious respiratory and circulatory dysfunction,abnormal blood routine and blood biochemical indexes before surgery; 2. Suffering from severe neuropsychiatric diseases; 3. People suffering from infectious diseases; 4. Taking benzodiazepines or opioids intermittently every day for 1 month or for nearly 3 months; 5. Allergies or contrains to benzodiazepines, opioids, propofol and other drugs and their drug components; 6. Patients judged to have difficulty in airway management: modified Markov score III or above; 7. Patients participating in other clinical trials; 8. Patients considered by the investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs change;Induction time of anesthesia;Wake up of time;Incidence of depression; | — |
Countries
China
Contacts
Public ContactChen Jiejuan
The Affiliated Hospital of Guizhou Medical University
Outcome results
None listed