Skip to content

Clinical study of plasma biomarkers in patients with chronic pain with cognitive impairment

Clinical study of plasma biomarkers in patients with chronic pain with cognitive impairment

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047290
Enrollment
Unknown
Registered
2021-06-11
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic Pain

Interventions

chronic pain combined with cognitive impairment group:No
Control Group:No

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Voluntary enrollment in this study and willingness to follow up; 2. Aged 18 years or older, regardless of gender; 3. VAS > 0 ; 4. Pain duration> 3 months.

Exclusion criteria

Exclusion criteria: 1.Poor general condition, inability to objectively describe symptoms, or inability to cooperate voluntarily with severe infections, respiratory failure, heart failure, etc; 2.Prior diagnosis of dementia, Alzheimer's disease, cerebral ischemia, brain injury, central infection, epilepsy, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and spinal cerebellar ataxia; 3.Have a mental illness previously diagnosed as major anxiety disorder, major depressive disorder, schizophrenia, etc; 4.Undergoing hemodialysis; 5.Severe anemia; 6.Suspected or confirmed drug and alcohol abuse; 7.Pregnancy or breastfeeding; 8.Other conditions that the investigators considered could not be included.

Design outcomes

Primary

MeasureTime frame
exosome;

Secondary

MeasureTime frame
Visual analog scale;Brief Pain Scale;Montreal Cognitive Inventory;Hamilton Anxiety Inventory;Hamilton Depression Inventory;Non-coding RNAs;

Countries

China

Contacts

Public ContactChen Chan

West China Hospital, Sichuan University

380893588@qq.com+86 18980606260

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026