Skip to content

Comparison of Segmentectomy Versus Lobectomy for Early-Stage Non-Small Cell Lung Cancer <= 2 cm in the Middle 1/3 of Lung Field: A Prospective and Multi-Center RCT Study

Comparison of Segmentectomy Versus Lobectomy for Early-Stage Non-Small Cell Lung Cancer <= 2 cm in the Middle 1/3 of Lung Field: A Prospective and Multi-Center RCT Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047249
Enrollment
Unknown
Registered
2021-06-11
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Experimental group:Segmentectomy with lymph node sampling
Control group:Lobectomy with lymph node sampling

Sponsors

Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patient aged 18 to 75 years; 2. 6 mm = 1 L and >= 70%); 7. Both lung segmentectomy and lobectomy could achieve R0 resection; 8. No serious cardiopulmonary complications, and could withstand both lung segmentectomy and lobectomy; 9. No hilus pulmonis and mediastinal lymph node metastasis and no distant metastasis; 10. Written informed consent; 11. Single tumor nodule or the concomitant nodule < microinvasive tumor.

Exclusion criteria

Exclusion criteria: 1. The tumor is located in right middle lobe; 2. A history of other malignancies in the last 5 years (exclusion of early-staged thyroid cancer and cervical cancer in situ); 3. Have received preoperative anti-tumor therapy, including prior chemotherapy, radiation therapy, target therapy and so on; 4. Serious mental illness; 5. Pregnant and lactating women; 6. Congestive heart failure, myocardial infarction, severe stenosis of coronary artery within recent 6 months; 7. With the history of cerebral infarction or cerebral hemorrhage within 6 months; 8. With the history of sustained systemic corticosteroid therapy within 1 month; 9. Other unsuitable situations.

Design outcomes

Primary

MeasureTime frame
Disease-free survival;

Countries

China

Contacts

Public ContactChen Liang

Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University

clbright0909@njmu.edu.cn+86 13913872727

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026