Hemodialysis
Conditions
Interventions
Experimental group:Citrate dialysate dialysis
Control group:Acetate dialysate
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients who are currently undergoing hemodialysis treatment, aged 18 years and above; 2.The vascular access is unobstructed, and the blood flow is >= 200ml/min; 3.Indications for heparin-free dialysis (mainly refers to recent surgery, internal bleeding); 4.Normal patients who are able to communicate both verbally and in writing; 5.Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Hypocalcemia; 2. Hypersensitivity to citric acid; 3. Liver dysfunction (ALT or AST levels more than twice the upper limit); 4. Abnormal coagulation indicators: activated partial thromboplastin time (APTT) is significantly prolonged (10 more than normal controls) Seconds or more), platelets (PLT) < 50x10^9/L; 5. Anticoagulant drugs or continuous antithrombotic therapy have been used within 24 hours before treatment; 6. Malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation conditions; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reaction; | — |
Countries
China
Contacts
Public ContactChen Lin
West China Hospital, Sichuan University
Outcome results
None listed