Targeting of SPP1 by microRNA-181b-5p promotes breast cancer cell epithelial–mesenchymal transition through the PI3K/AKT signaling pathway

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100047222

Enrollment

Unknown

Registered

2021-06-11

Start date

2021-06-11

Completion date

Unknown

Last updated

2022-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Case series:No

Eligibility

Sex/Gender

Female

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Receive multimodal ultrasound examination within 2 weeks before surgery; 2. Ultrasound showed that the maximum diameter of solid breast lesions was <=3.50 cm; 3. All patients participating in this study gave informed consent and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Have taken any anti-tumor related treatment before surgery; 2. Biopsy, surgery or other special treatments have been done before ultrasound examination.

Design outcomes

Primary

Measure	Time frame
SPP1 expression;microRNA-181b-5p expression;Relative protein expression;Ultrasound image information of the mass;	—

Countries

China

Contacts

Public ContactRen Weidong

Shengjing hospital, China medical university

renwdcmu@163.com+86 18940259190

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026