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The therapeutic effects of sequential and conservative management for medication-related osteonecrosis of the jaw

The therapeutic effects of sequential and conservative management for medication-related osteonecrosis of the jaw

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047208
Enrollment
Unknown
Registered
2021-06-10
Start date
2021-06-10
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medication-related osteonecrosis of the jaw

Interventions

stage 2 MRONJ group:NA
stage 3 MRONJ group:NA

Sponsors

Shanghai Ninth People’s Hospital, Collage of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center of Oral Disease
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Comply with MRONJ diagnostic criteria: (1) Seizures appear in the jaws, and the exposure time lasts for more than 8 weeks; (2) Are or have been treated with bisphosphonate drugs; (3) The jaw has not received radiotherapy. 2. MRONJ staging is 2 or 3 stages; 3. MRONJ patients who are willing to accept conservative treatment with conservative sequences.

Exclusion criteria

Exclusion criteria: Patients with developmental maxillofacial anomalies, previous radiation in the head and neck area and jaw bone tumors were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Epidemiological data;Surgical method and postoperative curative effect;

Countries

China

Contacts

Public ContactWang Shaoyi

Department of Oral Surgery, Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine

wangshaoyi163@aliyun.com+86 13917179943

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026