Acne scars
Conditions
Interventions
Experimental group1:Radiofrequency microneedle
Experimental group2:CO2 lattice laser
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 50 years (gender unlimited); 2. Atrophic scar after acne; 3. Acne activity; 4. Bilateral symmetry of acne scar; 5. No signs of infection such as ulcers, pus and exudation on the face; 6. The function of heart, lung, liver and kidney is normal; Can not have more than 2 kinds of heart, lung, liver, kidney function complications at the same time; 7. If there is diabetes, blood sugar control is normal; 8. Coagulation function is normal; 9. Stop taking isoretinoic acid capsules for at least 3 months; 10. Written informed consent signed by the patient or his legal agent; 11. Be able to follow up the research or follow-up process; Be able to observe adverse events and curative effect in cooperation.
Exclusion criteria
Exclusion criteria: 1. Active acne, the treatment site has a large number of pustules, cysts or nodules; 2. Fever (body temperature above 37.5 degree) or active infection with obvious influence on clinical trial; 3. There were skin tumors at the treatment site; 4. Scar constitution; 5. There was a history of sun exposure in recent one month; 6. Injection history of fillers in recent two weeks; 7. Grinding history in recent half a year; 8. Patients with malignant tumors of systemic organs and blood system and malignant tumors; 9. There was a history of HIV infection or HIV antibody positive, and there was a history of HSV attack in the treatment site in recent three months; 10. Low immune function and systemic failure; Patients with severe heart, liver, lung, kidney and other important organ diseases are not suitable for clinical trials, such as renal insufficiency requiring dialysis or kidney transplantation; 11, diabetic blood glucose control is bad (fasting blood glucose > 7.0mmol/L, postprandial 2 hour blood sugar > 11.1mmol/L, glycosylated hemoglobin A1C >6.5%); 12. Hematological diseases, including hematological tumors, coagulation disorders, hematopoietic dysfunction; 13. Addiction to drugs, tobacco and alcohol; 14. Have a clear history of mental illness; 15. Participated in the clinical study of any research drug within 1 month (or 5 half lives of the test drug) before enrollment; 16. Pregnant or lactating women; 17. Taking glucocorticoids or other immunosuppressants, anticoagulants, or suffering from autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne scar weight score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatological Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactLi Wei
Shanghai Dermatology Hospital
Outcome results
None listed